The anaphase-promoting complex: it's not just for mitosis any more
نویسندگان
چکیده
منابع مشابه
Regulation of mitosis - molecular analysis of the anaphase-promoting complex
Regulation of mitosis molecular analysis of the anaphase-promoting complex. Thesis by Pia-Marie Jörgensen, Department of Cell and Molecular Biology, Division of Molecular Genetics, Karolinska Institutet, S-171 77 Stockholm Cell division is achieved by the progression through a series of events known as the cell cycle. To make sure that the original cell is copied with high fidelity, an elaborat...
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The APC (anaphase-promoting complex) is a multisubunit E3 ubiquitin ligase that targets cell-cycle-related proteins for degradation by the 26 S proteasome. The APC contains at least 13 subunits and is regulated by the binding of co-activator proteins and by phosphorylation. It is not known why the APC contains 13 subunits when many other ubiquitin ligases are small single-subunit enzymes. In th...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 2002
ISSN: 0890-9369
DOI: 10.1101/gad.1013102